Desperate Housewives fans will be able to wish their favorite show goodbye this weekend at the Block Party for Wisteria Lane, benefiting the Cystic Fibrosis Foundation.

Featuring honorary Chairman James Denton and a performance by the star-studded Band From TV, the charity party will raise money for the Cystic Fibrosis Foundation, and will allow you to explore the neighborhood where the show is filmed, enjoy an old-fashioned barbecue from a stonefire grill, take part in a silent auction and rub shoulders with celebrities.

Last year’s event attracted a plethora of stars, including Marcia Cross, Dana Delany, Nathan Fillion, Greg Grunberg, Teri Hatcher, Bob Guiney, Jon Huertas, Felicity Huffman, Adrian Pasdar, Vanessa Williams and many more.

The event takes place on Saturday, April 21, at the Universal Studios Back Lot, 6:30pm. Tickets are $250, and more information is available here.

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